Sookmyung Women's University

 

 

Laboratory of Bioinformatics and Molecular Design

  

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  Major Publications                         Click here to see the  complete list of publications

 

  Computer-aided drug design

  1. Identification of (b-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor g activity , Jiwon Choi, Yoonae Ko, Huisun Lee, Yunsun Park, Young Yang, Kwang-Hwi Cho and Sukjoon Yoon, European Journal of Medicinal Chemistry, 45: 193-202 (2009)
  2. Optimization of high throughput virtual screening by combining shape-matching and docking methods, Huisun Lee, Jiwon Choi, Irina Kufareva, Ruben Abagyan, Anton Filikov, Young Yang and Sukjoon Yoon, Journal of Chemical Information and Modeling, 48(3): 489-497 (2008)
  3. Surrogate Docking: Structure-based virtual screening at high throughput speed, Sukjoon Yoon, Andrew Smellie, Dave Hartsough and Anton Filikov Journal of Computer-aided Molecular Design, 19(7):483-497 (2005)
  4. Identification of minimal subset of receptor conformations for improved multiple conformation docking method and two-step scoring, Sukjoon Yoon and William J. Welsh, Journal of Chemical Information and Computer Sciences (JCICS), 44(1), 88-96 (2004)

 

  Omics and Systems Medicine

  1. Integrative cell line modeling for profiling genotype-dependent drug sensitivity , Sukjoon Yoon et al., In preparation
  2. Global analysis of microarray data reveals intrinsic properties in gene expression and tissue selectivity , Changsik Kim, Jiwon Choi, Hyunjin Park, Yunsun Park, Jungsun Park, Kwanghwi Cho, Taesung Park, Young Yang and Sukjoon Yoon, Bioinformatics, In press (2010)
  3. Large scale data mining approach for the gene-specific standardization of microarray gene expression data, Sukjoon Yoon and Young Yang, Jiwon Choi and Jeeweon Seong, Bioinformatics, 22(23), 2898-904 (2006)

 

  Amyloid fibril prediction and Protein bioinformatics

  1. NetCSSP: web application for predicting chameleon sequences and amyloid fibril formation, Changsik Kim, Jiwon Choi, Seong Joon Lee, William J. Welsh and Sukjoon Yoon, Nucleic Acids Research, 37:W469-73 (2009)
  2. CSSP2: An improved method for predicting contact-dependent secondary structure propensity, Sukjoon Yoon, William J. Welsh, Heeyoung Jung and Young Do Yoo, Computational Biology and Chemistry, 31(5-6), 373-377 (2007)
  3. Rapid assessment of contact-dependent secondary structure propensity: relevance to amyloidogenic sequences, Sukjoon Yoon and William J. Welsh, PROTEINS: Structure, Function and Bioinformatics, 60(1), 110-117 (2005)
  4. Detecting hidden sequence propensity for amyloid fibril formation, Sukjoon Yoon and William J. Welsh, Protein Science, 13(8), 2149-2160 (2004)

 

  Miscellaneous

  1. Transposon-directed base-exchange mutagenesis (TDEM): a novel mothod for multiple-nucleotide substitutions within a target gene, YC Kim, Huisun Lee, Sukjoon Yoon and SL Morrison, Biotechniques, 46(7): 534-42 (2009)
  2. Qhelix: a computational tool for the improved measurement of inter-helical angles in proteins, Huisun Lee and Sukjoon Yoon, Protein J, 26(8), 556-561 (2007)
  3. Improved method for predicting beta-turn using support vector machine, Qidong Zhang, Sukjoon Yoon and William J. Welsh, Bioinformatics, 21(10), 2370-2374 (2005)